Chronic Trace · Inc. Dover, Delaware · MMXXVI

The laboratory test 
for the brain. 

Cardiology has its troponin. Endocrinology has its A1C. Brain health has, until now, depended on what the patient says or what the observer sees. Chronic Trace turns a single video capture into objective indices, scored against a personal baseline, so recovery and return-to-play or return-to-duty become decisions you can see, not guess.

Software-as-a-Medical-Device in development. Nine U.S. patents pending. Manipulation-resistant by architecture.

9:41
Chronic Trace
Cohort · 09 May
New capture
Recent subjects
S-04-217
MMA · Active
Baseline current
S-06-118
Ukraine · Civilian
Re-capture due
S-06-119
Ukraine · Soldier
Baseline current
S-04-203
Pre-shift · Aviation
New baseline
Capture
Cohort
Indices
Active data collection

On the ground, today.

01United States
Mixed Martial Arts
Sub-concussive exposure capture with active fighters between competition windows.
02Ukraine
Civilian & Soldier Cohort
Combat-zone and civilian-displacement cohorts; blast and impact exposure.
Platform pathways
SportDefense & VAPharmaceutical TrialsPre-HospitalTelepsychiatry
0
Biomarker domains
0
Single multimodal capture
0
U.S. patents pending
0
Active field cohorts

Chronic Trace is a research-stage platform, positioned as a decision-support tool only. It is not diagnostic; results require clinical interpretation, and clinical decisions remain with licensed healthcare professionals.

For partners, researchers, and operators

Request 
access. 

Chronic Trace is invitation-led during pivotal validation. Tell us about your program and we'll respond within one business day.

What you'll see
  • Thirty-second capture on a device the subject already owns
  • Multiple involuntary signal domains fused into one calibrated index
  • Manipulation-resistant by architecture — saccades, pupils, retinal vasculature
  • Personal baseline comparison, not population averages

Information shared here is held in confidence and used only to evaluate fit for partnership or pilot.

Where the platform operates

Five pathways. 
One capture. 

The same thirty-second capture serves indications across sport, defense, pharmaceutical trials, pre-hospital stroke triage, and outpatient behavioral health. The science is shared. The pathways differ.

Pathway 01

Sport, Occupational, and Insurance

Team, league, and fitness-for-duty programs.

Pre-participation baselines, sub-concussive exposure monitoring, return-to-play decision support, and pre-shift readiness for safety-critical work. Captures the slow-accumulation signal that subjective checklists miss.

Personal baselinesSub-concussive monitoringFitness-for-duty
Active or planned cohorts
  • Mixed Martial Arts · active fighters
  • Lacrosse · collegiate
  • Aviation · pre-shift

Cohort names reflect ongoing data-collection programs and research collaborations. No identifiable subject data is shown.

How a capture works

One short capture. 
Anyone can run it. 

No clinic, no wearable, no training. A health worker, a coach, a parent: anyone runs the full capture and reads one calibrated index at the end. Here is the whole protocol, the way the instrument reads it.

One capturesingle clip
Five signalsinvoluntary + task-based
One readingpersonal baseline
Phase 01 · Setup

Open & begin

BEGIN

Pick the person and tap begin. The whole capture runs on the phone they already own. No clinic, no wearable, no calibration step.

ReadsRuns on-device
Phase 02 · Postural

They stand still

SWAY · 33 KEYPOINTS

Standing naturally, arms relaxed at their sides. The camera reads the involuntary postural sway no one can consciously suppress.

ReadsPostural sway·33-point skeletal
Phase 03 · Ocular + Autonomic

They follow a dot

SACCADES · rPPG · HRV

Their eyes track a moving target while heart-rate variability is lifted from the same facial video. Two involuntary systems, one clip, nothing fakeable.

ReadsSaccadic latency·rPPG · HRV
Phase 04 · Cognitive

They connect the trail

12345678TRAIL · ONCOGNITIVE TRAIL · ATTENTION UNDER LOAD

A short, timed cognitive trail. Number to number under light time pressure: attention under load. (Operator can swap Trail-Making for Stroop per session.)

ReadsCognitive trail·Stroop optional
Phase 05 · Reaction Time

They tap on cue

SRT · LIVEWAIT…TAP248MS

A single response area waits gray, then flashes. The subject taps as fast as they can. Millisecond-precision latency per trial under randomized inter-stimulus intervals so the timing can't be paced.

ReadsSimple RT·False-start guard
FusionThe reading
CapturePosturalOcular + AutonomicCognitiveReaction TimeOne index
0
/100CLI
Within personal baseline

Every signal folds into one Concussion Likelihood Index, measured against this person's own baseline.

A decision-support signal, not a diagnosis. Clinical decisions remain with licensed professionals.

§  Platform · eleven signal domains

Eleven domains. 
One coherent signal. 

A single short capture, processed on the device the subject already owns, lifts involuntary physiological signal and task-based performance metrics across the platform's eleven biomarker domains. None of the involuntary streams can be consciously modulated.

Five domains are live in production today, two run in research mode while we promote consumer-camera artifacts to clinical-grade, and four are on the engineering pipeline. Our Dispersion-Based Cognitive Intra-Individual Variability (d-CIIV) framework fuses the live signal into a calibrated, longitudinally-comparable family of indices.

Live todayResearch modeRoadmap
Live in production05 domains

Oculomotor function

Saccadic latency and peak velocity, antisaccade error rate, smooth pursuit gain, fixation stability, nystagmus characterization.

Postural sway & motor kinematics

33-point skeletal landmark tracking, sway amplitude and frequency, pronator drift, gait kinematics where ambulation is permitted.

Cognitive performance

Trail-Making (number-to-number under time pressure) or Stroop interference, operator's choice per session. Path efficiency, error rate, completion latency, per-condition slowing.

Reaction time & psychomotor performance

Simple reaction time at millisecond precision with randomized inter-stimulus intervals so timing can't be paced. False-start detection and a deliberate-slowing flag at the trial level.

Remote photoplethysmography

Heart-rate variability extracted from facial skin video — RMSSD, SDNN, HF/LF/LF:HF ratios; atrial-fibrillation detection from RR irregularity.

Research mode02 domains

Pupillary autonomics

Baseline diameter, light-reflex amplitude and latency, constriction velocity, pupillary unrest under steady illumination.

Bilateral asymmetry indices

Computed across all foregoing domains; in EEG-integrated embodiments, frontal alpha asymmetry as a primary depression biomarker.

On the pipeline04 domains

Retinal vascular imaging

The only non-invasive optical window to live CNS microvasculature — arteriovenous color ratio, vessel caliber, pulsation rhythm.

Voice & speech acoustics

Prosodic flattening, fundamental-frequency contour, articulation rate, jitter, shimmer, dysarthria detection, semantic coherence.

Facial micro-expressions

468-point face mesh at 30+ fps, bilateral activation symmetry, central-versus-peripheral discrimination, blink rate and duration.

Sleep & circadian biomarkers

In wearable-integrated deployments, sleep architecture, fragmentation, REM latency, and circadian phase.

Manipulation-resistance, by construction
An individual cannot, by force of will, alter the latency of a saccadic eye movement, the constriction velocity of the pupil to a light flash, the diameter of a retinal arteriole, the cardiac rhythm, or the involuntary postural corrections of stance maintenance.
Chronic Trace Whitepaper · May 2026
00
U.S. patents pending
00 / 00
Domains live · mapped
Single clip · 5 phases
Capture · protocol

Software-as-a-Medical-Device platform under development. All indices described are research-stage and positioned as decision-support only — not diagnostic. Results require clinical interpretation, and clinical decisions remain with licensed healthcare professionals.

Every domain folded into a continuous score relative to the subject's own baseline. Slide to see how each band is interpreted. The CLI is a decision-support signal, not diagnostic; results require clinical interpretation.

A single calibrated index

The Concussion 
Likelihood Index. 

14/100
Within personal baseline
003969100

Indices coherent with the subject's own prior captures.

Interpretation bands
Questions

Worth 
asking. 

If something here doesn't resolve your question, a real person responds within one business day.

Get in touch

One technology, one capture, one patent moat, pointed at the last major domain of medicine without an objective test. Reserve a non-binding allocation before the offering opens.

Invest

Back the laboratory 
test for the brain. 

Closing the gap

Cardiology has its troponin. 
Now the brain has one too. 

A thirty-second video, on the camera in your pocket — a family of calibrated, manipulation-resistant indices for the last major domain of medicine without an objective biomarker.